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罗格列

网络rosiglitazone

罗格列

罗格列

罗格列

rosiglitazone

常用药物为罗格列 (rosiglitazone)和匹格列酮(pioglitazone)。 PPAR2C 活性可能有由抗炎作用，TZDs 可能对防治动脉粥样硬 …

1

We did not observe similar associations in a secondary analysis evaluating pioglitazone.

我们在第二次罗格列酮分析评估中没有看到类似的相关性。

2

Rosiglitazone was taken off the market in Europe , and its use is greatly restricted in the United States .

罗格列酮已经撤出欧洲市场，在美国的使用也被大大限制。

4

Rosiglitazone and pioglitazone are part of a group of drugs called thiazolidinediones .

罗格列酮和吡咯列酮同属噻唑烷二酮类。

5

When rosiglitazone was first authorised in the EU in 2000 , it was contraindicated in patients with a history of cardiac failure .

2000年欧盟首次批准使用罗格列酮时，就其应用于心衰病史患者身上就存在着争议。

6

Daily cost of glibenclamide and metformin was low , and gliquidone was medium and rosiglitazone was expensive .

格列本脲、二甲双胍每日药费较低，格列喹酮价格适中，罗格列酮属价格较高品种。

7

Individual domain scores for mood, ophthalmologic symptoms, and fatigue were also significantly more improved by insulin glargine.

情绪、眼部症状和疲劳的单项评分在甘精胰岛素治疗组的提高程度也显著高于罗格列酮治疗组。

8

The aim of this meta-analysis of randomized clinical trials is to assess the effect of rosiglitazone on the incidence of cancer .

这项对随机临床试验荟萃分析的目的是评价罗格列酮对肿瘤发生率的影响。

9

International Diabetes : Do rosiglitazone and pioglitazone have different or similar properties in respect to their cardiovascular profiles?

《国际糖尿病》：罗格列酮和吡格列酮对心血管的影响是否有所差别？二者有何相似性？

10

Has some of the bad press and issues with rosiglitazone unfairly affected pioglitazone?

有关罗格列酮的一些负面新闻是否会对吡格列酮有影响？

11

International Diabetes : Does pioglitazone have more favorable effects on serum lipids than rosiglitazone ?

《国际糖尿病》：吡格列酮对血脂的作用是否优于罗格列酮？

15

most of the fractures seen in the women taking rosiglitazone affected bones in the upper arm , hand , or foot .

所观察到的罗格列酮组女性患者发生骨折的最常见部位是上臂、手和足。

16

CONCLUSION Rosiglitazone maleate possesses the insulin sensitizing effect and could be used in the treatment of type 2 diabetes .

结论罗格列酮具有胰岛素增敏作用，对 2 型糖尿病有治疗作用。

17

During that time , women taking rosiglitazone were more likely to have bone fractures than women taking either metformin or glyburide .

随访期间，罗格列酮组的女性患者骨折发生率明显高于二甲双胍组和格列本脲组。

18

Adjusting for potential confounding factors , individuals on rosiglitazone had 15% higher rate of death and 13% higher risk of heart failure .

调整潜在的混杂因素后，服用罗格列酮的病人比服用匹格列酮的病人的死亡率高 15%，心衰风险高 13%。

20

This may apply to drugs other than rosiglitazone also , but our experience was specifically with rosiglitazone .

这可能也适用于罗格列酮以外的药物，但我们的经验是罗格列酮专有的。

22

No difference between rosiglitazone and pioglitazone was apparent .

罗格列酮和匹格列酮间无明显差别。

24

OBJECTIVE : To observe the effects of PA on IL-6 secretion and the influences of rosiglitazone (RSG) on them in cultured human adipocytes .

目的：观察软脂酸（PA ）对糖尿病及非糖尿病人成熟脂肪细胞分泌 IL-6 的影响及罗格列酮（RSG ）干预的效果。

25

Beginning in 1999 , rosiglitazone maleate and pioglitazone hydrochloride were approved for use .

从 1999年开始，马来酸罗格列酮和盐酸匹格列酮被批准使用。

26

Rosiglitazone increases the sensitivity of cells to insulin .

罗格列酮可以增加细胞对胰岛素的敏感性。

27

28

The misconduct began in the late 1990s and continued , in the case of Avandia 's safety data, through to 2007 .

这种不当行为始于上世纪九十年代末，在有关罗格列酮的案件上一直持续到 2007 年。

29

Patients taking pioglitazone averaged 380 days of medication , and patients taking rosiglitazone averaged 369 days of medication.

服用匹格列酮的病人平均进行了 380 天的治疗，服用罗格列酮的病人平均进行了 369 天的治疗。

30

What is the mechanism of the synergy between rosiglitazone and carboplatin ?

罗格列酮与卡铂协同作用的机制是什么呢？

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